Dramatic Decrease in Malaria Transmission after Large-Scale Indoor Residual Spraying with Bendiocarb in Benin, an Area of High Resistance of Anopheles gambiae to Pyrethroids

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Entomological baseline data on malaria transmission and susceptibility of Anopheles gambiae to insecticides in preparation for Indoor Residual Spraying (IRS) in Atacora, Benin

To implement indoor residual spraying (IRS), the department of Atacora was selected in Benin. Entomological surveys were performed before IRS implementation. Mosquitoes were sampled by Pyrethrum spray catch and were identified morphologically and by molecular methods. The Plasmodium falciparum circumsporozoite indices were measured by enzyme linked immunosorbent assay (ELISA). Molecular detecti...

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BACKGROUND Recently the use of indoor residual spraying of insecticide (IRS) has greatly increased in Africa; however, limited data exist on the quantitative impacts of IRS on health outcomes in highly malaria endemic areas. METHODOLOGY/PRINCIPAL FINDINGS Routine data were collected on more than 90,000 patient visits at a single health facility over a 56 month period covering five rounds of I...

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Alternative Treatments for Indoor Residual Spraying for Malaria Control in a Village with Pyrethroid- and DDT-Resistant Vectors in The Gambia

BACKGROUND Malaria vector control is threatened by resistance to pyrethroids, the only class of insecticides used for treating bed nets. The second major vector control method is indoor residual spraying with pyrethroids or the organochloride DDT. However, resistance to pyrethroids frequently confers resistance to DDT. Therefore, alternative insecticides are urgently needed. METHODOLOGY/PRINC...

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Reduced Efficacy of Insecticide-treated Nets and Indoor Residual Spraying for Malaria Control in Pyrethroid Resistance Area, Benin

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Anopheles gambiae s.l. (Diptera: Culicidae) in Muleba, Tanzania has developed high levels of resistance to most insecticides currently advocated for malaria control. The kdr mutation has almost reached fixation in An. gambiae s.s. in Muleba. This change has the potential to jeopardize malaria control interventions carried out in the region. Trends in insecticide resistance were monitored in two...

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ژورنال

عنوان ژورنال: The American Journal of Tropical Medicine and Hygiene

سال: 2011

ISSN: 0002-9637,1476-1645

DOI: 10.4269/ajtmh.2011.10-0668